Fig. 5. Effect of PF on the protein expression of IDE and NEP in Aβ25–35-treated C6 glial cells. ‘Control’ represents non-treated cells, ‘Aβ’ represents Aβ25–35-treated cells, ‘PF1’, ‘PF5’, or ‘PF10’ represent the 3 concentrations of paeoniflorin treatment (1, 5, and 10 μg/mL, respectively) in Aβ25–35-treated cells. Values are mean ± SD.
IDE, insulin degrading enzyme; Aβ, amyloid beta; PF, paeoniflorin; NEP, neprilysin.
a-cMeans with different letters are significantly different (P < 0.05) as determined by Duncan's multiple range test.