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. 2020 Nov 19;12:11845–11855. doi: 10.2147/CMAR.S267666

Figure 4.

Figure 4

NEAT1 knockdown inhibited the proliferation, migration and invasion of gastric cancer AGS cells in vitro. AGS cells were also transfected with NEAT1 targeted siRNA (si-NEAT1), negative control siRNA (si-NC), pcDNA3.1-NEAT1 overexpression vector (pcDNA-NEAT1) and blank vector plasmid (pcDNA-3.1), respectively. (A) The expression levels of NEAT1 and miR-1224-5p were explored via RT-qPCR. (B) Cell proliferation was tested by CCK-8 assay. (C and D) Cell invasion was detected by transwell assay. (DF) Cell migration were detected by wound healing assay. Data are shown as mean ± SD. **P < 0.01.