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Panel A shows the number of T lymphocytes (CD3+) and panel B the number of B lymphocytes (CD19+) at baseline and two and six weeks after oral therapy with fingolimod. In Panel C, data are expressed as percentage of pre-treatment levels. Control mice received saline. Groups of four female mice, aged 12 weeks. The experiment was repeated twice with similar results, with a total of nine treated and nine control mice in these depletion experiments.
