Table 3.
Results for normal bone marrow myelogram in the study cohort of 236 donors based on counting by three independent investigators (200 cells each, in total 600 cells). The right part of this table shows the results from previous reports for comparison
| Lineage and maturation | This study | Wintrobe (2009) | Bain (1996) | Diem (2012) | |||
|---|---|---|---|---|---|---|---|
| Range (%) | Reference range (%) | Median (%) | Mean (%) | Mean (%) | Mean (%) | Mean (%) | |
| Erythroblasts (total) | 8.5–56.5 | 15.8–46.2 | 32.0 | 31.7 | 25.6 | 23.0 | |
| Male | 11.0–54.5 | 16.2–46.6 | 33.0 | 32.4 | 28.1 | ||
| Female | 8.5–56.5 | 15.6–45.0 | 29.5 | 30.1 | 22.5 | ||
| Proerythroblast | 0–5.0 | 0–3.0 | 0.5 | 0.6 | 0.6 | <1.0 | |
| Basophilic | 0–21.0 | 0.5–13.5 | 3.5 | 4.5 | 1.4 | 1.0 | |
| Polychromatophilic | 3.0–47.0 | 7.8–34.5 | 20.0 | 20.2 | 21.6 | 2.0 | |
| Orthochromatic | 0–21.0 | 0.5–16.5 | 5.5 | 6.3 | 2.0 | 19.0 | |
| Granulocytes (total) | 24.5–72.5 | 34.8–66.3 | 49.5 | 49.9 | |||
| Male | 26.0–70.5 | 35.5–64.5 | 49.5 | 49.7 | |||
| Female | 24.5–72.5 | 34.1–67.4 | 50.0 | 50.5 | |||
| Neutrophils (total) | 53.6 | 55.0 | |||||
| Myeloblast | 0–8.5 | 0–5.0 | 1.5 | 1.6 | 0.9 | 1.4 | 2.0 |
| Promyelocyte | 0–8.5 | 0–5.5 | 1.0 | 1.3 | 3.3 | 7.8 | 2.0 |
| Myelocyte | 1.0–31.7 | 5.8–24.0 | 13.5 | 13.7 | 12.7 | 7.6 | 3.0 |
| Metamyelocyte | 0.5–18.0 | 1.0–12.0 | 4.5 | 5.0 | 15.9 | 4.1 | 9.0 |
| Band | 2.0–34.0 | 6.5–26.2 | 14.5 | 15.2 | 12.4 | 32.1(m), 37.4(f) | 10.0 |
| Segmented | 1.0–27.5 | 2.5–19.7 | 9.5 | 9.8 | 7.4 | 29.0 | |
| Eosinophils (total) | 0–18.0 | 0.5–7.0 | 2.5 | 3.0 | 3.1 | 3.5 | 4.0 |
| Basophils (and mast cells) | 0–3.0 | 0–1.5 | 0 | 0.3 | <0.1 | 0.1 | <1.0 |
| GE-ratio | 0.5–5.9 | 0.8–4.1 | 1.6 | 1.7 | |||
| Monocytes | 0–8.5 | 0–6.0 | 2.0 | 2.2 | 0.3 | 1.3 | <1.0 |
| ME ratio | 0.6–6.2 | 0.8–4.1 | 1.6 | 1.8 | 2.3 | ||
| Male | 0.6–6.1 | 0.8–4.0 | 1.6 | 1.8 | 2.1 | ||
| Female | 0.6–6.2 | 0.8–4.2 | 1.7 | 2.0 | 2.8 | ||
| Lymphocytes | 1.0–38.5 | 5.5–23.2 | 13.2 | 13.6 | 16.2 | 13.1 | 13.0 |
| Plasma cells | 0–17.5 | 0–7.0 | 2.3 | 2.6 | 1.3 | 0.6 | 1.0 |
The calculation of GE (granulopoiesis/erythropoiesis) and ME (myelopoiesis/erythropoiesis) ratios included all stages of maturation in the individual lines: myeloblast to segmented granulocyte for G, plus monocytes for M, and proerythroblast to orthochromatic erythroblast for E, respectively. m male, f female