Table 5.
Impact of investigators on test results
| Lineage and maturation | ICC | Krippend alpha |
|---|---|---|
| Cellularity | 0.012 | 0.3822 |
| Megakaryopoiesis | 0.000 | 0.3270 |
| Erythroblasts (total) | 0.027 | 0.3483 |
| Proythroblast | 0.356 | − 0.1292 |
| Basophilic | 0.582 | − 0.1699 |
| Polychromatophilic | 0.311 | 0.0130 |
| Orthochromatic | 0.108 | − 0.0300 |
| Granulocytes (total) | 0.011 | 0.3409 |
| Myeloblast | 0.233 | 0.0242 |
| Promyelocyte | 0.530 | − 0.1691 |
| Myelocyte | 0.196 | 0.0823 |
| Metamyelocyte | 0.346 | − 0.0881 |
| Band | 0.292 | − 0.0093 |
| Segmented | 0.275 | 0.1271 |
| Eosinophils | 0.009 | 0.3410 |
| Basophils | 0.049 | 0.0179 |
| Monocytes | 0.412 | − 0.0854 |
| Lymphocytes | 0.059 | 0.2528 |
| Plasma cells | 0.132 | 0.2070 |
*IC-intra class correlation
Krippend alpha-Krippendorff’s alpha
Krippendorff’s alpha characterizes interrater reliability. A value of zero indicates perfect random disagreement, whereas a value of 1.0 indicates perfect agreement. Alpha can be negative when investigators consistently disagree, use different coding instructions or having conflicting understanding of them
Intra-class-correlation (ICC) estimates the proportions of variance due to the investigators. A value of zero indicates no impact; a value of 1.0 indicates that the investigators only explain variances