Table 3.

The influence of selected factors on the risk of PFS and OS shortening in multivariate analysis (Cox logistic regression model) (model adjustment for PFS: p < 0.0001; χ² = 41.40 and OS: p < 0.0001; χ² = 44.24)

Variable	Progression free survival				Overall survival
	β	p	HR	95% CI	β	p	HR	95% CI
Sex
Male	− 0.17	0.6935	0.84	0.35–1.99	2.56	0.0012	12.88	2.75–60.34
Age
≥ 65	0.80	0.1090	2.22	0.84–5.86	0.81	0.1331	2.24	0.79–6.39
Translocation t(4;14)
Present	2.72	< 0.0001	15.18	4.98–46.26	1.35	0.0218	3.84	1.22–12.07
Auto HSCT
No	0.10	0.8333	1.11	0.43–2.82	0.98	0.0745	2.65	0.91–7.71
Stage of chronic kidney disease
G3a/G3b/G4/G5D	− 1.28	0.0864	0.28	0.06–1.19	1.47	0.1016	4.35	0.75–25.03
Weight loss before treatment
Yes	0.75	0.2039	3.34	1.06–10.53	2.43	0.0001	11.39	3.50–37.08
ALB
Low	1.24	0.0021	3.47	1.58–7.64	1.19	0.0235	3.28	1.18–9.11
Creatinine
High	1.75	0.0112	5.73	1.50–21.95	−0.07	0.9198	0.93	0.22–3.98
NLR
High	1.34	0.0048	3.83	1.51–9.71	1.61	0.0133	5.00	1.41–17.75
PLR
High	− 0.62	0.1787	0.54	0.22–1.32	0.94	0.0496	2.56	1.01–6.51