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. 2020 Nov 23;11:5928. doi: 10.1038/s41467-020-19774-x

Table 3.

Non-hematological adverse events within 4 weeksa.

Total (%) Grade 3–4(%)
CRS 39 (83.0) 11 (23.4)
ICANS 2 (4.3) 1 (2.1)
ALT/AST increased 10 (21.3) 2 (4.3)
CRE increased 2 (4.3) 0
APTT/PT prolonged 10 (21.3) 0
Fibrinogen decreased 5 (10.6) 0
Acidosis 1 (2.1) 0
Hypokalemia 4 (8.5) 1 (2.1)
Hypoglycemia 2 (4.3) 0
Cephalalgia 2 (4.3) 0
Myalgia 2 (4.3) 0

aAccording to the CTCAE grading system by the United States National Cancer Institute38, and ASBMT Consensus Grading for Cytokine Release Syndrome and Neurologic Toxicity Associated with Immune Effector Cells39.

CRS represents cytokine release syndrome, ICANS immune effector cell-associated neurotoxicity syndrome, ALT alanine aminotransferase, AST aspartate aminotransferase, CRE creatinine, APTT activated partial thromboplastin time, PT prothrombin time.

Source data is provided as a Source Data file or available at 10.6084/m9.figshare.13136078.v1.