Table 1.
The demographic characteristics of the NESDA cohort (at the 2-year follow-up).
| Clinical values | Current depression/anxietya (n = 819) | Remitted depression/anxietyb (n = 920) | Control group (n = 492) | P valuec |
|---|---|---|---|---|
| Mean age (SD) | 44.9 (12.3) | 44.5 (13.2) | 43.6 (14.6) | 0.22 |
| Age range (y) | 19–66 | 19–68 | 20–66 | |
| Female (%) | 552 (67.4%) | 606 (65.9%) | 291 (59.1%) | 0.008 |
| Mental disorder subgroups | ||||
| Depression | 520 (63.5%) | 758 (82.4%) | – | |
| Major depressive disorder | 475 (91.3%) | 745 (98.2%) | – | |
| Dysthymia | 198 (38.1%) | 210 (27.7%) | – | |
| Anxiety | 608 (74.2%) | 612 (66.5%) | – | |
| Panic disorder with agoraphobia | 107 (17.6%) | 130 (21.2%) | – | |
| Panic disorder without agoraphobia | 140 (23.0%) | 149 (24.3%) | – | |
| Social phobia | 306 (50.3%) | 266 (43.4%) | – | |
| Generalized anxiety disorder | 166 (27.3%) | 259 (42.3%) | – | |
| Agoraphobia without panic disorder | 125 (20.6%) | 109 (17.8%) | – | |
| Using psychiatric medication in recent 2 yearsd | 324 (39.6%) | 195 (21.1%) | 23 (4.7%) | |
| Somatic diseasesd | ||||
| Diabetes | 52 (6.3%) | 45 (4.9%) | 17 (3.5%) | 0.066 |
| Stroke | 12 (1.6%) | 17 (1.8%) | 12 (2.4%) | 0.42 |
| Arthritis or arthrosis | 193 (23.6%) | 160 (17.4%) | 86 (17.4%) | 0.002 |
| Chronic none specific lung disease | 118 (14.4%) | 110 (12.0%) | 45 (9.1%) | 0.019 |
| Rheumatism (fibromyalgia, SLE, rheumatoid arthritis) | 87 (10.6%) | 53 (5.8%) | 14 (2.8%) | <0.001 |
| Tumor | 50 (6.1%) | 64 (7.0%) | 27 (5.5%) | 0.52 |
| Ulcer | 16 (2.0%) | 10 (1.1%) | 2 (0.4%) | 0.047 |
| Intestinal disorders | 166 (20.3%) | 134 (14.6%) | 35 (7.1%) | <0.001 |
| Allergies (hay fever, eczema) | 267 (32.6%) | 312 (33.9%) | 140 (28.5%) | 0.22 |
| Thyroid disease (Graves disease, hyperthyroidism) | 35 (4.3%) | 35 (3.8%) | 17 (3.5%) | 0.76 |
| Head injury | 20 (2.4%) | 22 (2.4%) | 5 (1.0%) | 0.15 |
| Sickness 1 week prior to blood drawnd | ||||
| Fever | 38 (4.6%) | 42 (4.6%) | 18 (3.7%) | 0.69 |
| Cold | 233 (28.4%) | 252 (27.4%) | 135 (27.4%) | 0.87 |
aDepression and/or anxiety present in the 6 months prior to assessment.
bLifetime depression and/or anxiety diagnosis, but not in the 6 months prior to assessment.
ct test is used for comparing the age difference between groups and the chi-square test is used for comparison of gender, somatic diseases, and sickness prior to blood drawn between different groups.
dThe number is dependent on questionnaires when the answer is “yes”.