Table 2.
Summary of data in Fig. 4.
| TRPC5 variant | Residue in TRPC4/1/3/6/7 | EA EC50 (nM) | AM237 EC50 (nM) |
|---|---|---|---|
| Wild-type | 5.7 | 10.6 | |
| Q573T | Q/F/K/K/K | 260 | 110 |
| F576A | F/F/F/F/F | ≥1400 | No response up to 5 µM |
| W577A | W/W/W/W/W | 370 | No response up to 5 µM |
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