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. 2020 Nov 10;11:563750. doi: 10.3389/fphar.2020.563750

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Copyright © 2020 Man, Deng, Li, Ma, Yang, Yang, Zhou and Yan

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Detoxification of licorice (GC) on cisplatin (CP)-induced hepatotoxicity in rats. (A) Liver index in rats (n = 10). (B) Serum aspartate aminotransferase (AST) levels (n = 10). (C) Serum alanine aminotransferase (ALT) levels (n = 10). (D) HE histological staining of liver tissue (200×). (E) Liver histological score of histological staining (n = 10). The results are presented as the mean ± SD. Significant differences vs. those in the control group (^## p < 0.01) and those of the CP-treated group (^* p < 0.05; ^** p < 0.01) were determined by t-test.