Table 2.
Patient Demographics and clinical characteristics stratified by lactate level.
| Variables | All patients (n = 2859) | Lactate ≤ 3 (n = 1355) | Lactate > 3 (n = 1058) | p-value |
|---|---|---|---|---|
| Age (yr) | 57.3 ± 17.8 | 56.3 ± 17.7 | 59.1 ± 17.7 | < 0.01 |
| Male | 52.9% (1522) | 53.7% (727) | 54.2% (573) | ns |
| Time to antibiotic (min) | 184 ± 157 | 189 ± 156 | 155 ± 138 | < 0.01 |
| Total IVF (mL) | 2460 ± 1759 | 2266 ± 1588 | 3062 ± 1885 | < 0.01 |
| Mortality | ||||
| In hospital | 14.4% (411) | 8.9% (121) | 21.5% (227) | < 0.01 |
| 28 days (n = 2468) | 19.0% (469) | 12.6% (148) | 28.3% (261) | < 0.01 |
| Any ICU admission | 72.0% (2059) | 68.2% (924) | 81.1% (858) | < 0.01 |
| Intubated (ED) | 8.5% (241) | 4.0% (54) | 15.3% (161) | < 0.01 |
| ALI (SF ratio < 452) | 58.0% (1659) | 53.0% (718) | 64.7% (684) | < 0.01 |
| Vasopressor(s) | 7.2% (205) | 4.1% (55) | 11.6% (123) | < 0.01 |