TABLE 1.
Characteristics of patients in training cohort and validation cohorts.
| Features |
Training cohort |
Validation cohort |
||
| CGGA325 (n = 325) | CGGA693 (n = 693) | TCGA (n = 651) | Rembrandt (n = 475) | |
| Age | ||||
| ≤41 | 150 | 322 | 280 | 161 |
| >41 | 175 | 370 | 371 | 233 |
| NA | 0 | 1 | 0 | 81 |
| Gender | ||||
| Male | 203 | 398 | 375 | 203 |
| Female | 122 | 295 | 276 | 121 |
| NA | 0 | 0 | 0 | 151 |
| Histology | ||||
| A | 56 | 119 | 63 | 85 |
| O | 52 | 69 | 186 | 37 |
| AA | 62 | 152 | 131 | 47 |
| AO | 12 | 103 | 134 | 20 |
| GBM | 139 | 249 | 136 | 183 |
| NA | 4 | 1 | 1 | 103 |
| Grade | ||||
| I | 0 | 0 | 0 | 2 |
| II | 103 | 188 | 249 | 92 |
| III | 79 | 255 | 265 | 70 |
| IV | 139 | 249 | 136 | 181 |
| NA | 4 | 1 | 1 | 130 |
| IDH status | ||||
| Mutant | 175 | 356 | 428 | NA |
| Wild-type | 149 | 286 | 216 | NA |
| NA | 1 | 51 | 7 | NA |
| 1p/19q status | ||||
| Codel | 67 | 145 | 169 | 24 |
| Non-codel | 250 | 478 | 478 | 150 |
| NA | 8 | 70 | 4 | 301 |
| Chemotherapy | ||||
| Yes | 178 | 457 | NA | NA |
| No | 124 | 151 | NA | NA |
| NA | 23 | 85 | NA | NA |
| Radiotherapy | ||||
| Yes | 258 | 509 | NA | NA |
| No | 51 | 113 | NA | NA |
| NA | 16 | 71 | NA | NA |
A, astrocytoma; O, oligodendroglioma/oligoastrocytoma; AA, anaplastic astrocytoma; AO, anaplastic oligodendroglioma/oligoastrocytoma; GBM, glioblastoma multiforme; IDH, isocitrate dehydrogenase.