Fig. 8. TDP-43 oligomers colocalize with amyloid plaques in the brain of an AD patient.

a Representative immunostaining micrographs reveal that TDP-43 oligomers mainly colocalized with intraneuronal Aβ (arrowhead) and partly with amyloid plaque (arrow). b Representative immunostaining micrographs show that both amyloid plaque (arrow) and intraneuronal Aβ (arrowhead) colocalized with the total TDP-43 in the entorhinal cortex of a 77-year-old patient with Braak stage IV AD. Four induvial samples were performed. Source data are provided as a Source Data file.