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. 2020 Nov 23;10:20389. doi: 10.1038/s41598-020-77429-9

Table 4.

Adjusted odds ratiosa and 95% confidence intervals for foetal acidosis based on gestational weight gain with vaginal deliveries according to Japanese criteria28.

BMI category (kg/m2) Gestational weight gain
Insufficient Appropriate Excessive
UmA-pH < 7.2
Group 1; BMI < 18.5 (n = 9321) n = 4664 n = 2871 n = 1786
 aOR (95% CI) 0.85 (0.70–1.04) Ref 1.03 (0.81–1.30)
Group 2; BMI 18.5–< 20.0 (n = 14,752) n = 5261 n = 5294 n = 4197
 aOR (95% CI) 0.97 (0.83–1.15) Ref 1.12 (0.94–1.32)
Group 3; BMI 20.0–< 23.0 (n = 22,703) n = 5807 n = 8099 n = 8797
 aOR (95% CI) 0.95 (0.82–1.08) Ref 1.00 (0.88–1.12)
Group 4; BMI 23.0–< 25.0 (n = 5942) n = 802 n = 2015 n = 3125
 aOR (95% CI) 0.84 (0.58–1.22) Ref 1.31 (1.04–1.62)
Group 5; BMI ≥ 25 (n = 5627) n = 597 n = 1767 n = 3263
 aOR (95% CI) 0.82 (0.57–1.19) Ref 0.97 (0.78–1.21)
UmA-pH < 7.1
Group 1; BMI < 18.5 (n = 9321) n = 4664 n = 2871 n = 1786
 aOR (95% CI) 1.30 (0.78–2.16) Ref 1.49 (0.81–2.74)
Group 2; BMI 18.5–< 20.0 (n = 14,752) n = 5261 n = 5294 n = 4197
 aOR (95% CI) 1.04 (0.69–1.57) Ref 1.46 (0.97–2.18)
Group 3; BMI 20.0–< 23.0 (n = 22,703) n = 5807 n = 8099 n = 8797
 aOR (95% CI) 0.83 (0.60–1.14) Ref 0.96 (0.73–1.26)
Group 4; BMI 23.0–< 25.0 (n = 5942) n = 802 n = 2015 n = 3125
 aOR (95% CI) 1.42 (0.59–3.42) Ref 2.08 (1.13–3.83)
Group 5; BMI ≥ 25 (n = 5627) n = 597 n = 1767 n = 3263
 aOR (95% CI) 0.29 (0.09–0.97) Ref 0.80 (0.49–1.31)

Logistic regression models were used to calculate the adjusted odds ratios and 95% confidence intervals for UmA-pH < 7.20 and for UmA-pH < 7.10, with women with appropriate gestational weight gain as the reference. BMI body mass index, UmA-pH umbilical artery pH.

aAdjusted for maternal age, maternal education, annual household income, maternal smoking during pregnancy, parity, preterm birth and small-for-gestational age infants.