Table 5.
IC50 (µg/mL) of CE and fractions from A. cearensis seeds against C. albicans strains
| Evaluated combination | CA INCQS 40006 | CA URM 4127 |
|---|---|---|
| FCZ | 2.4 ± 1.2 | 7.68 ± 4.8 |
| CE—A. cearensis | > 2048 ± 3.6 | > 2048 ± 3.2 |
| FR-1—A. cearensis | 1968.6 ± 9.5 | 1138.4 ± 4.8 |
| FR-2—A. cearensis | 1173.3 ± 8.1 | 1273.3 ± 6.3 |
| FR-3—A. cearensis | 123.5 ± 5.5 | 45.6 ± 6.1 |
| CE—A. cearensis + FCZ | 9.54 ± 4.0 | 3.14 ± 2.0 |
| FR-1—A. cearensis + FCZ | 3.51 ± 2.5 | 2.41 ± 1.8 |
| FR-2—A. cearensis + FCZ | 2.1 ± 0.99 | 1.81 ± 0.8 |
| FR-3—A. cearensis + FCZ | 11.9 ± 8.7 | 18.8 ± 7.4 |
CA Candida albicans, FCZ fluconazole, CE aqueous crude extract, FR-1 fraction 1, FR-2 fraction 2, FR-3 fraction 3, MIC minimum inhibitory concentration, INCQS National Institute of Health Control, URM University Recife Mycology—P ≤ 0.05 in relation to FCZ control