Table 2.

Differential immune genes between high-TMB and low-TMB groups.

Gene	Low group	High group	FC	logFC	P value	FDR
REG3G	0.404	2.489	0.162	−2.624	0.005	0.028
CXCL14	10.127	44.060	0.230	−2.121	<0.001	0.002
SLPI	14.781	50.258	0.294	−1.766	0.001	0.007
DEFB1	1.712	7.033	0.243	−2.039	0.006	0.031
PAEP	233.441	53.848	4.335	2.116	0.011	0.049
CRABP2	15.835	37.732	0.420	−1.253	<0.001	<0.001
PI15	5.623	11.346	0.496	−1.013	0.010	0.044
ELN	2.116	4.364	0.485	−1.044	<0.001	<0.001
PLA2G2A	3.254	7.884	0.413	−1.277	<0.001	<0.001
SYTL1	0.936	2.093	0.447	−1.162	0.002	0.014
EDN3	18.306	37.586	0.487	−1.038	<0.001	0.002
SEMA3D	1.346	2.931	0.459	−1.122	<0.001	<0.001
BMP6	1.117	2.712	0.412	−1.280	<0.001	<0.001
CSPG5	1.564	3.153	0.496	−1.012	<0.001	0.001
DKK1	6.221	3.043	2.045	1.032	0.002	0.012
FGF5	0.582	0.062	9.433	3.238	0.001	0.011
GAL	1.961	4.915	0.399	−1.326	<0.001	<0.001
IL33	2.748	5.718	0.481	−1.057	<0.001	0.002
ADCYAP1R1	0.132	0.313	0.422	−1.246	0.001	0.007
CNTFR	1.635	4.071	0.402	−1.316	<0.001	<0.001
FGFR2	0.179	0.755	0.238	−2.073	<0.001	<0.001
FGFR3	0.616	4.900	0.126	−2.992	<0.001	0.001
LGR5	0.111	0.600	0.185	−2.432	0.001	0.011
VIPR1	0.086	0.406	0.212	−2.240	<0.001	0.002
MAP3K8	1.090	2.284	0.478	−1.066	0.002	0.013

TMB, tumor mutation burden; FC, fold change; FDR, false discovery rate.