Table 1.
Datasets of PINK1 expression in pan-cancers. (ONCOMINE database).
| Cancer Site | Types of Cancer vs Normal | Fold change | t-test | P-value | Dataset |
|---|---|---|---|---|---|
| Seminoma | Yolk Sac Tumor | -6.696 | -24.724 | 1.29E-12 | Korkola et al. (17) |
| Embryonal Carcinoma | -3.791 | -16.357 | 1.03E-12 | ||
| Teratoma | -3.779 | -17.980 | 1.53E-12 | ||
| Mixed Germ Cell Tumor | -3.918 | -16.049 | 4.27E-17 | ||
| Seminoma | -3.389 | -10.774 | 9.78E-9 | ||
| Esophagus | Esophageal Squamous Cell Carcinoma | -2.679 | -12.671 | 9.12E-14 | Hu et al. (18) |
| Barrett’s Esophagus | -2.045 | -4.595 | 2.58E-5 | Hao et al. (19) | |
| Esophageal Adenocarcinoma | -2.019 | -4.466 | 2.70E-4 | Kimchi et al. (20) | |
| Esophageal Adenocarcinoma | -3.056 | -11.823 | 6.24E-21 | Kim et al. (21) | |
| Colorectum | Rectal Adenocarcinoma | -3.871 | -20.458 | 2.12E-29 | TCGA |
| Colon Adenocarcinoma | -4.081 | -24.383 | 6.17E-28 | ||
| Colon Mucinous Adenocarcinoma | -3.457 | -13.849 | 4.66E-16 | ||
| Cecum Adenocarcinoma | -4.264 | -13.980 | 2.83E-15 | ||
| Rectosigmoid Adenocarcinoma | -5.819 | -15.085 | 4.25E-4 | ||
| Colorectal Carcinoma | -2.062 | -11.954 | 1.57E-16 | Skrzypczak et al. (22) | |
| Colon Adenoma | -3.673 | -22.192 | 1.89E-9 | ||
| Colon Adenoma Epithelia | -2.394 | -12.066 | 1.11E-8 | ||
| Colon Adenocarcinoma | -4.095 | -3.358 | 9.92E-4 | Notterman et al. (23) | |
| Rectal Adenocarcinoma | -2.276 | -11.718 | 6.51E-21 | Gaedcke et al. (24) | |
| Leukemia | Acute Myeloid Leukemia | -3.934 | -7.825 | 2.14E-6 | Stegmaier et al. (25) |
| Lymphoma | Diffuse Large B-Cell Lymphoma | 2.109 | 14.511 | 1.63E-17 | Compagno et al. (26) |
| Brain | Anaplastic Oligoastrocytoma | -2.669 | -5.793 | 2.12E-4 | Bredel et al. (27) |
| Glioblastoma | -3.621 | -10.427 | 4.76E-6 | ||
| Brain Giloblastoma | -3.149 | -20.046 | 2.49E-10 | TCGA | |
| Glioblastoma | -2.608 | -11.474 | 9.35E-17 | Sun et al. (28) | |
| Glioblastoma | -2.439 | -9.730 | 3.32E-4 | Murat et al. (29) | |
| Breast | Ductal Breast Carcinoma | -2.051 | -8.074 | 1.63E-8 | Richardson et al. (30) |
| Head-Neck | Head and Neck Squamous Cell Carcinoma | -2.040 | -8.657 | 1.80E-10 | Ginos et al. (31) |
| Liver | Hepatocellular Carcinoma | -2.060 | -5.582 | 3.88E-6 | Roessler et al. (32) |
| Melanoma | Cutaneous Melanoma | -2.116 | -9.098 | 7.14E-6 | Talantov et al. (33) |
| Ovary | Ovarian Serous Adenocarcinoma | -2.557 | -7.469 | 1.81E-7 | Yoshihara et al. (34) |