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. 2020 Nov 17;15:2991–3001. doi: 10.2147/COPD.S280614

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© 2020 Zhang et al.

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HAT1 negatively regulated TLR4 and inflammatory cytokine expression. (A) HAT1 expression in NR8383 cells after transfection with different siRNAs; the most significant inhibition of HAT1 expression was observed with si-HAT1 697. (B) The expression of HAT1 in NR8383 cells after transfection with si-HAT1 697 or overexpression of HAT1 using a vector. (C) IL-6, IL-8, TNF-α, and IFN-γ levels in NR8383 cells after transfection with si-HAT1 697. *P < 0.05; **P < 0.01; ***P < 0.001.