Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Nov 23;10:20382. doi: 10.1038/s41598-020-77290-w

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Photobiomodulation protects retinal structure and prevents photoreceptor cell loss. (a) compares the total retinal thickness in SD, P23H and 830 nm treated P23H rats. (b) compares ONL thickness from SD-OCT linear scans (1000 A-scans/B-scan, 80 B-scans) in sham and PBM-treated P23H rats. Total retinal thickness was significantly (p < 0.05) greater in the 830 nm-PBM treated group compared to the sham-treated P23H group and SD control group. The ONL thickness of 830 nm PBM treated group (filled triangle) derived from Longitudinal Reflectivity Profile (LRP) was significantly greater (F_(1,8) = 12.23, p < 0.01) compared to the sham-treated group (filled circle) across the entire scan. Error bars: SEM. (c) compares the representative images of retinal sections, stained with toluidine blue for the sham-treated group and the NIR-PBM-treated group. The photoreceptor nuclei (ONL) in the 830 nm PBM-treated group were more organized and symmetrically packed compared to the sham-treated photoreceptor nuclei, which were disrupted and disorganized. (d) shows the quantitative analyses of the ONL thickness sampled across the retina from the superior to the inferior edge (n = 4). ONL thickness in the 830 nm PBM-treated P23H group is significantly greater compared to the sham-treated P23H group. Error bars: SEM.