Table 2.
Distribution of GC genotypes and diplotypes by ethnicity
| Total (n = 217) |
Malay, Indians & others (n = 197) |
Chinese (n = 20) |
χ2 | p-value | ||
|---|---|---|---|---|---|---|
| GC rs4588 | ||||||
| Allele | G | (79.5) | (81.0) | (65.0) | 4.909 | 0.015 |
| T | (20.5) | (19.0) | (35.0) | |||
| Genotype | GG | 135 (62.2) | 127 (64.5) | 8 (40.0) | ||
| GT | 76 (35.0) | 66 (33.5) | 10 (50.0) | |||
| TT | 6 (2.8) | 4 (2.0) | 2 (10.0) | |||
| GC rs7041 | ||||||
| Allele | A | (63.4) | (62.0) | (77.0) | 3.793 | 0.051 |
| C | (36.6) | (38.0) | (23.0) | |||
| Genotype | AA | 89 (41.0) | 78 (39.6) | 11 (55.0) | ||
| AC | 97 (44.7) | 88 (44.7) | 9 (45.0) | |||
| CC | 31 (14.3) | 31 (15.7) | 0 | |||
| GC diplotypes (rs4588 + rs7041) | ||||||
| Allele | 1f | (43.1) | (43.1) | (42.5) | 6.934 | 0.031 |
| 1 s | (36.6) | (38.1) | (22.5) | |||
| 2 | (20.3) | (18.8) | (35.0) | |||
| Diplotypes | 1f-1f | 44 (20.3) | 40 (20.3) | 4 (20.0) | ||
| 1s–1s | 31 (14.3) | 31 (15.7) | 0 (0.0) | |||
| 1f-1s | 60 (27.6) | 56 (28.4) | 4 (20.0) | |||
| 1f-2 | 39 (18.0) | 34 (17.3) | 5 (25.0) | |||
| 1s-2 | 37 (17.1) | 32 (16.2) | 5 (25.0) | |||
| 2–2 | 6 (2.8) | 4 (2.0) | 2 (10.0) | |||
Categorical variables are presented as n (percentages).