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Effect of 3d in 6 Hz mouse seizure models.
| Seizure model | Time of test | ED50 value (mg/kg) | 95% confidence interval (mg/kg) |
|---|---|---|---|
| 6 Hz 32mA mouse model | 1 h | 152.7 | 98.6–211.0 |
| 6 Hz 44mA mouse model | 1 h | 263.7 | 198.9–321.8 |
| MES model | 1 h | 108.1 | 70.4–152.9 |
| s.c. PTZ mouse model | 1 h | 349.2 | 256.0–432.1 |
