Table 2.
Characteristics of major NPSLE patients visiting the clinic between 2007–2018.
| Clinical characteristics | Major NPSLE (n = 149) |
|---|---|
| NPSLE phenotype (n, %) | |
| Inflammatory | 57 (38) |
| Ischemic | 48 (32) |
| Combined | 44 (30) |
| NPSLE syndrome (n, %*) | |
| Aseptic meningitis | 5 (2) |
| Cerebrovascular disease | 85 (33) |
| Demyelinating syndrome | 0 (0) |
| Headache | 10 (4) |
| Movement disorder (chorea) | 5 (2) |
| Myelopathy | 13 (5) |
| Seizure disorders | 15 (6) |
| Acute confusional state | 7 (3) |
| Anxiety disorder | 1 (0) |
| Cognitive dysfunction | 49 (19) |
| Mood disorder | 14 (6) |
| Psychosis | 8 (3) |
| AIDPa | 0 (0) |
| Autonomic disorder | 1 (0) |
| Mononeuropathy | 1 (0) |
| Myasthenia gravis | 0 (0) |
| Neuropathy, cranial | 7 (3) |
| Plexopathy | 1 (0) |
| Polyneuropathy | 7 (3) |
| Otherb | 26 (10) |
*% of total neuropsychiatric symptoms (n = 255)
aAcute inflammatory demyelinating polyneuropathy.
bOther NPSLE symptoms: cerebral vasculitis (n = 10), organic brain syndrome (n = 4), pyramidal tract disorder (n = 3), visual disturbance other than optic neuritis (n = 2), apraxia (n = 2), walking disorder (n = 2), motor disorder left arm (n = 1), mononeuritis multiplex (n = 1), increased intracranial pressure (n = 1).