Table 4.
Cause-specific mortality in patients presenting with neuropsychiatric symptoms attributed to SLE (major NPSLE) or to mild and other causes (minor/non-NPSLE).
|
Major NPSLE (n = 13) |
Minor/non-NPSLE (n = 17) |
|||||
|---|---|---|---|---|---|---|
| n a | % | SMR b | n a | % | SMR b | |
| Infections | 3 | 23 | 91.3 (18.8 – 266.9) | 2 | 12 | 29.0 (3.5 – 104.9) |
| Cardiovascular diseasec | 0 | 0 | 0.0 (0.0 – 13.7) | 5 | 29 | 6.2 (2.0 – 14.6) |
| Malignancies | 3 | 23 | 2.7 (0.6 – 7.8) | 4 | 24 | 2.3 (0.6 – 5.9) |
| SLE | 3 | 23 | – | 0 | 0 | – |
| NPSLE | 0 | 0 | – | – | – | – |
| Otherd | 2 | 15 | – | 3 | 18 | – |
| Unknown | 2 | 15 | – | 3 | 8 | – |
aNumber of deaths.
bStandardized mortality ratio, ratio of the observed and expected number of deaths and 95% confidence intervals.
cCardiac arrest (n = 4), stroke (n = 1).
dOther (major NPSLE): extra-abdominal hemorrhage (psoas hematoma) (n = 1), bowel perforation (n = 1). Other (minor/non-NPSLE): Alzheimer disease (n = 1), intra-abdominal hemorrhage (n = 1), suicide (n = 1).