Figure 1.
Multiple sequence alignment of 4 strains of CoV (Bat-CoV, SARS-Cov-2, SARS-CoV and MERS-CoV) RdRp Sequences. Green colour highlighted indicated identical residues while brown and red colour highlighted residues are less conserved. The black dashed rectangles mark active site aspartates while blue rectangles mark the residues lying in the 5 Å region surrounding the active aspartates. The alignment was made using the Clustal omega web server and Jalview software.