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. 2020 Nov 10;23(1):43. doi: 10.3892/mmr.2020.11681

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Copyright: © Gong et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 6. — Association between disease activity and miRNA-155-5p/miRNA-125b-5p in activated CD4⁺ T cells from patients with pSS. (A) Proliferation of CD4⁺ T cells, (B) number of CD4⁺ IFN-γ⁺ cells, (C) supernatant IFN-γ secretion and expression levels of (D) miRNA-155-5p and (E) miRNA-125b-5p in CD4⁺ T cells were in patients with inactive (ESSDAI ≤2; n=6) and active disease (ESSDAI >2; n=6) from pSS activation and MSC treatment groups. Data are presented as the mean ± SEM. *P<0.05. miRNA, microRNA; pSS, primary Sjögren syndrome; ESSDAI, EULAR Sjögren's syndrome disease activity index; MSC, mesenchymal stem cell; ns, not significant.