Table 2.
Study participants in Figure 1c
| Healthy controls (HC) | Asymptomatic malaria (AS) | Uncomplicated malaria (UM) | Severe malaria (SM) | P‐value a | |
|---|---|---|---|---|---|
| Number, n | 7 | 6 | 20 | 11 | |
| Age, years [median (IQR)] | 30 (25–35) | 21 (18–25) | 33 (25–41) | 25 (23–36) | 0.0208 |
| Males, number (%) | 6 (86) | 6 (100) | 13 (65) | 7 (64) | |
|
Parasitaemia (parasites µL−1) [median (IQR)] |
0 (0–0) | 85 (62–6956) | 2048 (374–7113) | 176 758 (91 786–508 775) | < 0.0001 |
| HRP2 (ng mL−1) b | 0.03 (0.03–0.03) | 0.3 (0.3–3.1) | 34 (0.3–109.6) | 5691 (3651–12 247) | 0.0003 |
|
Haemoglobin (g dL−1) |
12 (11–16) | 11 (9.5–13.25) | 11 (10–12.75) | 9 (8–12) | 0.1142 |
|
Angiopoietin‐2 (pg mL−1) [median (IQR)] |
2511 (1940–3465) | 3255 (2666–4698) | 3181 (2144–3911) | 25 025 (5300–42 177) | < 0.0001 |
All values are median (interquartile range) unless otherwise indicated.
a
Kruskal–Wallis test.
b
Samples below the detection limit were assigned the value of half the detection limit (0.03 pg mL−1).