Skip to main content
. 2012 Apr 12;103(6):1010–1021. doi: 10.1111/j.1349-7006.2012.02262.x

Figure 2.

Figure 2

Mutation of the APC gene causes the development of adenoma in the digestive tract. (A) SW480 colorectal cancer cells expressing truncated APC and SW480 transfectants expressing full‐length APC were subjected to immunohistochemical analysis with anti‐β‐catenin antibody. Representative images are shown. Green, β‐catenin. Magnification, ×200. (B) SW480 cells expressing truncated APC and SW480 transfectants expressing full‐length APC were subjected to Western blot analysis with anti‐APC antibody and anti‐β‐actin antibody. Representative images are shown. (C) Small intestinal tissue was collected from APC min/+ mice with non‐polyp and polyp lesions and C57BL/6J mice and subjected to H&E staining. Representative images are shown. Magnification, ×100.