FIGURE 5.

Effects of treatments on cardiac function. Canagliflozin was associated with improved systolic and diastolic function compared to baseline. Specifically, we observed improvements in left ventricular ejection fraction (LVEF), A, and deceleration time (DT), B. When compared to sitagliptin at time_x_group interaction analysis, however, the difference in LVEF was no longer statistically significant, while the difference with DT remained statistically significant. Data are presented as mean ± SD for LVEF, and median and interquartile ranges for DT. MD, mean difference between groups