Table 1.
AFM13 dose levels (mg/kg) | Pembrolizumab (mg) | |||
---|---|---|---|---|
Weeks 2 and 3 | Weeks 4-9 | Weeks 10, 13, 16, 19, 22, 25 | Weeks 1-52 Q3W* | |
Cohort 1 | 0.1 × 3 | 0.5 | 0.5 | 200 |
Cohort 2 | 0.5 × 3 | 1.5 | 1.5 | 200 |
Cohort 3 | 3.0 × 3 | 7.0 | 7.0 | 200 |
Q3W, once every 3 weeks.
Until disease progression, unacceptable toxicity, cessation of treatment because of complete response (at investigator’s discretion) or 52 weeks of treatment, whichever occurred first.