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. 2020 Nov 20;13:12015–12025. doi: 10.2147/OTT.S279723

Table 1.

KEGG Enrichment Top 11 Signaling Pathway

Pathway Description NO. P value GENE ID
Ribosome 13 1.54787E-10 RPLP2/RPL17/RPL3/RPL27/RPS6/RPL19/RPL21/RPL13/RPS8/RPL18/RPL35/RPS2/RPL8
Spliceosome 11 1.88672E-08 HNRNPK/HNRNPU/HNRNPA3/DDX46/PCBP1/HNRNPA1/SRSF3/HNRNPC/DDX5/HNRNPM/SRSF2
Cell cycle 8 1.99324E-05 MCM5/MCM7/MCM4/CDK1/MCM6/YWHAG/MCM2/PRKDCa
DNA replication 5 2.23215E-05 MCM5/MCM7/MCM4/MCM6/MCM2b
Viral carcinogenesis 9 0.000326665 CDK1/PSMC1/HNRNPK/YWHAG/DDX3X/SND1/CHD4/RANBP1/HIST1H4A;HIST1H4B;HIST1H4C;
HISTIH4D/HISTIH4E/HISTIH4F/HIST1H4H/HISTIH4J;HISTIH4K;HIST1H4L;HIST2HA;HIST2H4B;HIST4H4
Biosynthesis of amino acids 5 0.000848813 PYCR1/IDH3A/CPS1/PFKP/PHGDH
Epstein-Barr virus infection 8 0.003970254 CDK1/PSMD12/PSMC1/PSMC3/YWHAG/SND1/XPO1/HSPB1
Carbon metabolism 5 0.004100065 CPS1/IDH3A/PHGDH/PFKP/HK2
RNA transport 6 0.007360002 EIF4G1/EEF1A1/EIF4G2/XPO1/RANGAP1/EIF4A1
HIF-1 signaling pathway 4 0.016269678 HMOX1/ELOC/RPS6/HK2
Proteoglycans in cancer 5 0.044286847 CTTN/DDX5/PDCD4/FLNA/RPS6

Notes: aDifferential expression levels of MCM family members were enriched in the cell cycle. bDifferential expression levels of MCM family members were enriched in DNA replication pathways.