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. 2020 Nov 24;16(11):e1008376. doi: 10.1371/journal.pcbi.1008376

Table 1. Semantic knowledge bases containing information about organism characteristics.

Name* Description or Scope Format Pattern Reference
Biodiversity
Phenoscape Vertebrate morphology OWL in RDF Blazegraph triplestore EQ [35,60]
EOL TraitBank Internet aggregator of data about species Neo4j Character/Character State [61,62]
Microbial Phenotypes Wiki Web-based community resource designed to display microbial phenotypes and the methods used to study them. MediaWiki Tabular, uses OMP [63] [64]
PolyTraits Database on biological traits of polychaetes Relational database Character/Character State [65,66]
TRY Global database of curated plant traits Relational database Map traits to TOP (EQ) [67] [34]
FuTRES Functional traits of vertebrates OWL in RDF triplestore Measurement-Based quantitative data, trait definitions follow EQ pattern from OBAEQ [68]
Planteome Plant genomics and phenomics GAF and SOLR EQ and DOS-DP [69]
Global Plant Phenology Aggregator of plant phenological data OWL and JSON Measurement-Based quantitative and presence/absence data; EQ model [70,71]
Semantic Morph·D·Base Repository for morphological data OWL in RDF triplestore Measurement-Based with connection to TBox: Phenotype Knowledge Graphs [7276]
TaxonWorks Web-based workbench for taxonomists and biodiversity scientists PostgreSQL (relational database) Class (OTU) or Measurement-Based (collection object). Qualitative, quantitative, statistical, media, gene, text, presence/absence, arbitrary triples (data attributes). [77]
World Register of Marine Species Authoritative classification and catalogue of marine species MS SQL relational database with trait module Character/Character State [78]
Agriculture
Gramene Comparative functional genomics in crops and model plant species MongoDB JSON-like, using PO [79] [80,81]
Sol Genomics Network Clade-oriented database dedicated to the biology of the Solanaceae family Relational database (chado) Tabular, dbxref to PO [82,83]
GrainGenes Comprehensive resource for molecular and phenotypic information for wheat, barley, rye, and other related species, including oat. Relational database (chado) Tabular, using Plant TO [84] [85,86]
Annex Cereals ontology OWL Measurement and Class-based [87]
CassavaBase Genomic and phenomic resource for cassava Relational database (chado) Tabular, uses CO [88] [89,90]
AgroLD Integrated data about commercially important plants RDF triples EQ and DOS-DP [91]
Biomedicine and Model Organisms
Monarch Initiative, uPheno, and Human Phenotype Ontology Integrator of cross species genotype-phenotype data including human phenotypes and their relationship to diseases OWL EQ and DOS-DP [28,92,93]
MGI Mouse genomic and phenomic resource OWL and OBO EQ and DOS-DP [94,95]
WormBase Nematode genomic and phenomic resource OWL and OBO EQ and DOS-DP [96,97]
TAIR Arabidopsis genomic and phenomic resource OWL and OBO EQ and DOS-DP [98,99]
FlyBase Fruit fly genomic and phenomic resource OWL and OBO EQ and DOS-DP [100,101]
XenBase Xenopus genomic and phenomic resource OWL and OBO EQ and DOS-DP [102,103]
ZFIN Zebrafish genomic and phenomic resource OWL and OBO EQ and DOS-DP [104,105]
Saccharomyces Genome Database Comprehensive integrated biological information for the budding yeast Saccharomyces cerevisiae PostgreSQL Tabular, uses APO [106] [107]
RGD Structured and standardized data for 8 species (rat, mouse, human, chinchilla, bonobo, 13-lined ground squirrel, dog, and pig) Relational database (chado), GAF, and OBO Qualitative, links QTLs to multiple OBO phenotype ontologies [108,109]

*To be included in this table, a resource must contain annotations linking traits to organisms, use a phenotype ontology, and not require login credentials.

Includes phenotype data reported at the individual specimen level.

Includes phenotype data reported at the group level.

APO, Ascomycete Phenotype Ontology; CO, Crop Ontology; DOS-DP, Dead Simple Ontology Design Pattern; EQ, Entity–Quality; GAF, GO Annotation File format; OBAEQ, Ontology of Biological Attributes-Entity Quality; OBO, Open Biomedical Ontologies format; OMP, Ontology of Microbial Phenotypes; OWL, Web Ontology Language; OTU, Operational Taxonomic Units; PO, Plant Ontology; QTL, Quantitative Trait Locus; RDF, Resource Description Framework; RGD, Rat Genome Database; TO, Trait Ontology; TOP, Thesaurus of Plant Characteristics.