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. 2020 Nov 24;15(11):e0242743. doi: 10.1371/journal.pone.0242743

Fig 4. GDM effect on 5’- and 5- deiodinase activity in human placenta.

Fig 4

Kinetic of deiodinase activity was measured as T3 or rT3 formation from T4 (0–500 nM, 37°C, 15 min) in placental tissue (300μg placental protein) from Normal Glucose Tolerant (NGT, ○) and Gestational Diabetes Mellitus (GDM, ●) pregnancies. In A and C, T3 and rT3 formation from T4 adjusted to Michaelis-Menten equation. In B and D, Eadie-Hofstee plot from data in A and C, respectively. Mean ± SEM. N = 9 per group.