Fig 2. Aggregation of plasma exosome-like vesicles by a SubX^™ reagent.

Particle size distribution in: the initial plasma pre-cleaned from cell debris (A); the supernatant (B) and resuspended pellet (C) obtained after incubation of precleaned plasma with SubX^™SubX and the first centrifugation at 10,000 g; the final pellet after the second round of centrifugation at 10,000 g and resuspension of the precipitate in a 300 mM solution of NaCl (D). Data obtained by dynamic light scattering (DLS). The X-axis is the hydrodynamic diameter of the particles in nm, the Y-axis is the contribution to the scattering in %.