FIG 2.

Serum vibriocidal antibody titers detected in cohort 1 of Sm-treated mice immunized with HaitiV (n = 5) (A) or formalin-inactivated HaitiV (n = 5) (B). Blood was obtained weekly from all mice and assayed to quantify circulating vibriocidal antibodies. Circles indicate the lowest dilutions at which specific vibriocidal activity was detected, and the heights of the bars represent geometric mean titers in each group. Ogawa V. cholerae PIC158 was used to measure Ogawa serotype-specific antibodies, and Inaba V. cholerae PIC018 was used to measure Inaba serotype-specific antibodies. Circulating serum antibodies below the limit of detection are indicated by open symbols. No vibriocidal antibody titers were detected in mice inoculated with the sodium bicarbonate vehicle.