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. 2020 Nov 23;20:560. doi: 10.1186/s12935-020-01660-7

Table 2.

List of natural compounds and their target genes as well as their expression in bladder cancer

Natural compound Cell line Target gene Expression References
Resveratrol T24, ECV-304 Bcl-2 Down-regulate [88, 89]
639Vs mTORC1 Down-regulate [93]
RT4, 5637, T24 Akt, mTOR, SRC Down-regulate [102, 103]
5637 Akt Down-regulate [105]
PTEN Up-regulate
Curcumin T24 P53 Down-regulate [118]
T24, J82, TCCSUP Akt, SRC Down-regulate [119]
EJ PI3K Suppress activation [126]
Paclitaxel T24 Akt Down-regulate [134]