Table 1. Electrophysiological properties of control and Zdhhc14 sh#1 (14 sh#1) AAV- infected hippocampal neurons.
Table 1—source data 1. Source data for Table 1.
elife-56058-table1-data1.xlsx (18.9KB, xlsx)
| Control AAV | 14sh#1 AAV | p-value | |
|---|---|---|---|
| Vhold (mV) | −63.14 +/− 1.53 | −63.13 +/− 1.30 | 0.67MW |
| Rheobase (mA) | 140.22 +/− 75.84 | 86.96 +/− 39.07 | **0.0052MW |
| Peak amplitude (mV) | 103.33 +/− 7.66 | 87.41 +/− 10.00 | ****0.00000028 |
| Half width (ms) | 2.68 +/− 0.50 | 3.02 +/− 0.94 | 0.18MW |
| Max rise slope (mV/ms) | 154.15 +/− 49.03 | 89.76 +/− 44.78 | ****<0.0001MW |
| Max decay scope (mV/ms) | −42.21 +/− 8.39 | −33.16 +/−9.90 | **0.0017 |
| Input resistance: −25 pA | 324.86 +/− 144.03 | 393.27 +/− 189.20 | 0.17 |
| −50 pA | 326.76 +/− 146.95 | 409.55 +/− 160.52 | 0.075 |
| −75 pA | 319.91 +/− 132.03 | 411.04 +/− 163.64 | *0.044 |
| −100 pA | 304.48 +/− 113.12 | 397.83 +/− 160.32 | *0.027 |
| Peak dV/dt | 133.62 +/− 40.47 | 85.45 +/− 41.07 | ***0.0002 |
| Anti-peak dV/dt | −37.62 +/− 7.99 | −32.11 +/− 9.56 | *0.038 |
| Resting membrane potential (mV) | −60.51 +/− 8.08 | −54.79 +/− 8.31 | *0.022 |
Mean +/− SD is shown; N = 23; data were analyzed using unpaired Student’s t-test unless otherwise indicated: MW=Mann Whitney test.