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. 2020 Nov 3;130(12):6222–6224. doi: 10.1172/JCI142081

Figure 1. Model for T cell response in COVID-19 relative to patient risk.

Figure 1

Patients at risk for severe COVID-19 disease (advanced age and higher comorbidity) show higher T cell responses than those at low risk. However, the activated T cells from patients at risk have impaired IFN-γ and enhanced IL-2 production.