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. 2020 Nov 3;130(12):6443–6456. doi: 10.1172/JCI126584

Figure 2. Proinflammatory cytokines increase, whereas C-KIT+ ICCs decrease, in the dilated colon of HAEC patients.

Figure 2

(A) Immunohistochemistry staining of ICCs of HSCR and HAEC patients for C-KIT. Scale bars: 100 μm. Data are representative of n = 75 samples of HSCR patients and n = 21 samples of HAEC patients. Arrows indicate C-KIT+ ICCs. (B) Western blotting of colon of HSCR and HAEC patients. (C) Semiquantitative analysis of protein expression levels, with each protein being normalized to β-actin. One-way ANOVA: ***P < 0.001.