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The expression of tight junction proteins is altered in bladder cancer (BC) tissues. Claudin-4 (a), ZO-1 (b), and ZONAB (c) expression was detected by immunohistochemical staining in adjacent nontumor tissues (ANTT) and BC tissues (original magnification ×400. Scale bar, 100 μm). The patient counts on high staining and low/moderate staining of tight junction protein in ANTT and BC is shown by stack bar plots (n = 53). ∗P < 0.05, Fisher's exact test.
