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The higher expression of SIRT3 and SIRT6 in the PCa patients. (a) mRNA expression levels of SIRT3/6/7 were found to be overexpressed in primary PCa tissues compared to normal prostate samples. ∗∗P < 0.01 and ∗∗∗P < 0.001. (b) Compared to the normal prostate tissues, the mRNA expression levels of SIRT3/6/7 in PCa samples were significantly correlated with the Gleason score; SIRT1/2/4/5 did not show consistent trend. ∗P < 0.01, ∗∗P < 0.01, and ∗∗∗P < 0.001.
