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. 2020 Nov 17;2020:9457101. doi: 10.1155/2020/9457101

Figure 7.

Figure 7

SE inhibited apoptosis of H/R-induced HK-2 cells by upregulating the mitochondrial damage-dependent-JNK expression to downregulate Caspase-3 expression, modulating the JNK/Caspase-3 signaling pathways. H/R: hypoxia/reoxygenation. The solid arrows represent positive feedback; the dotted arrows represent negative feedback. The red line represents the JNK/Caspase-3 signaling pathway; The green represents the action route of SE and target.