TABLE 1.
Categorical variable | All patients (n = 29) |
Macrolide susceptibility |
P value | ||||
---|---|---|---|---|---|---|---|
Susceptible (n = 9) |
Resistant (n = 20) |
||||||
n | % | n | % | n | % | ||
Gender | |||||||
Male | 13 | 44.8 | 6 | 66.7 | 7 | 35.0 | 0.2256 |
Female | 16 | 55.2 | 3 | 33.3 | 13 | 65.0 | |
M. abscessus subsp. | |||||||
abscessus | 17 | 58.6 | 0 | 0.0 | 17 | 85.0 | <0.001 |
massiliense | 10 | 34.5 | 9 | 100.0 | 1 | 5.0 | <0.001 |
bolletii | 2 | 6.9 | 0 | 0.0 | 2 | 10.0 | 1 |
Morphology | |||||||
Smooth | 18 | 62.1 | 7 | 77.8 | 9 | 45.0 | 0.1296 |
Rough | 11 | 37.9 | 2 | 22.2 | 11 | 55.0 | |
Manifestation | |||||||
NTM-PD/colonization | 28 | 96.6 | 9 | 100.0 | 19 | 95.0 | 1 |
ATS criteria fullfilled | 20 | 71.4 | 5 | 55.6 | 15 | 78.9 | 0.3715 |
Lymphadenitis | 1 | 3.4 | 0 | 0.0 | 1 | 5.0 | |
Disposition | |||||||
CF | 21 | 72.4 | 6 | 66.7 | 15 | 75.0 | 0.6749 |
HIV | 1 | 3.4 | 0 | 0.0 | 1 | 5.0 | |
SLD | 3 | 10.3 | 0 | 0.0 | 3 | 15.0 | |
Lung transplantation | 1 | 3.4 | 1 | 11.1 | 0 | 0.0 | |
Malignoma | 1 | 3.4 | 1 | 11.1 | 0 | 0.0 | |
None | 2 | 6.9 | 1 | 11.1 | 1 | 5.0 |
M. abscessus subsp. abscessus was the most frequent subspecies. All isolates except one originated from pulmonary samples. NTM-PD, NTM pulmonary disease; ATS, American Thoracic Society; CF, cystic fibrosis; HIV, human immunodeficiency virus; SLD, structural lung disease. P values in boldface are those that reached the significance level of α < 0.05.