FIG 2.

Neutralizing activity analysis of convalescent plasma (CP) donors. (A) Distribution of neutralization 50% inhibitory concentration (IC₅₀) values (NT₅₀, reciprocal plasma dilution) of convalescent donor plasma samples using HIV-1 (red) or VSV (blue) pseudovirus overexpressing the SARS-CoV-2 spike protein (S) (HIV-S and VSV-S, respectively). (B) Frequencies of convalescent plasma donor NT₅₀ values within indicated groups using HIV-S (top) or VSV-S (bottom) pseudovirus constructs. (C) Frequency distribution of convalescent plasma HIV-S NT₅₀ values versus age groups (years). n = 5 to 38; Kruskal-Wallis test. (D) Frequencies of convalescent plasma donor NT₅₀ values versus sex. n = 190; Mann-Whitney test; **, P < 0.01. (E) Frequencies of convalescent plasma donor NT₅₀ values versus blood group antigens. n = 15 to 82; Kruskal-Wallis test. (F) Frequencies of convalescent plasma donor NT₅₀ values versus time (days) since last reported symptom. n = 19 to 33; Mann-Whitney t test; *, P < 0.05.