TABLE 2.
Compound Muscle Action Potential Evaluation on the Right Leg After Intramuscular Injection With Different BoNT/A Preparations
| BoNT/A | Dose (U/kg) | No. of Animals (Responsive/Total) | CMAPmin (mV) | Duration of Action (d) | CMAPAAC (mV·d) |
| CBoNT | 3.3 | 15/15 | 2.59 ± 0.57* | 65.1 ± 15.1 | 1,379.24 ± 155.08* |
| 9.8 | 15/15 | 0.27 ± 0.09† | 120.4 ± 12.5* | 2,713.61 ± 336.70† | |
| OBoNT | 3.3 | 5/5 | 2.80 ± 1.07 | 54.4 ± 8.8 | 1,228.05 ± 168.37 |
| 9.8 | 5/5 | 0.24 ± 0.09† | 116.2 ± 17.0 | 2,657.01 ± 421.81† | |
| IBoNT | 3.3 | 5/5 | 3.96 ± 1.80 | 63.0 ± 17.6 | 1,174.36 ± 120.94 |
| 9.8 | 5/5 | 0.79 ± 0.19 | 104.2 ± 12.0 | 1854.75 ± 135.63 |
*
Data expressed as mean ± SD (p < .05, using 2-tailed t-test vs IBoNT).
†
Data expressed as mean ± SD (p < .01 using 2-tailed t-test vs IBoNT).
CMAPmin, lowest CMAP amplitude; CMAPAAC, Total CMAP reduction versus time.