Table 1.
Enriched GO category derived from STRING database.
| Description | Count in gene set | False discovery rate | |
|---|---|---|---|
| S100A6 downregulated protein | |||
| PFAM protein domains | |||
| Domain | |||
| PF00076 | RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) | 18 of 228 | 1.14e−10 |
| PF01423 | LSM domain | 6 of 21 | 4.77e−06 |
| PF00118 | TCP-1/cpn60 chaperonin family | 5 of 15 | 2.36e−05 |
| PF00183 | Hsp90 protein | 3 of 4 | 0.00078 |
| PF10417 | C-terminal domain of 1-Cys peroxiredoxin | 3 of 6 | 0.015 |
| (more…) | |||
| S100A6 upregulated protein | |||
| Reactome pathways | |||
| Pathway | |||
| MMU-75153 | Apoptotic execution phase | 11 of 48 | 1.18e−10 |
| MMU-109581 | Apoptosis | 12 of 93 | 2.02e−09 |
| MMU-211227 | Activation of DNA fragmentation factor | 7 of 13 | 5.58e−09 |
| MMU-2559584 | Formation of senescence-associated heterochromatin foci (SAHF) | 7 of 17 | 1.62e−08 |
| MMU-2559586 | DNA damage/telomere stress induced senescence | 9 of 51 | 1.90e−08 |
| (more…) | |||
(above) Changed proteins were mapped onto PFAM protein domain according to gene ontology classification system. (below) Changed proteins were mapped onto Reactome pathway according to gene ontology classification system.