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. 2020 Nov 11;7:585276. doi: 10.3389/fvets.2020.585276

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Copyright © 2020 Xu, Xie, Zhou, Hu, Gu, Yang, Zheng, Huang, Xu, Cai, Liu, Wu and Hong.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) The top 10 most abundant miRNAs in SP-EVs. Left axis and the bars: percentage of each miRNA of the total miRNA reads. Right axis and dot: cumulative percentage of miRNA reads. (B) qPCR analysis of miRNA expression in three additional SP-EV samples that had not been sequenced; four higher abundant and two lower abundant miRNAs (by sequencing data) were tested.