Table 2.

Biophysical parameters of the computational model of brainstem respiratory circuitry. The parameters ${\stackrel{-}{g}}_K,\mathrm{ }{\stackrel{-}{g}}_L,\mathrm{ }{\stackrel{-}{g}}_E$, and ${\stackrel{-}{g}}_I$ are the respective maximal conductances of a delayed rectifier potassium current, an ohmic leak current, an excitatory synaptic current, and an inhibitory synaptic current. The parameters E_K, E_Li, E_E, and E_I are the reversal potentials of the potassium current, leak current, excitatory synaptic current, and inhibitory synaptic current. The parameters ${\stackrel{-}{g}}_{NaP}$ and E_Na are the maximal conductance of the persistent sodium current and the reversal potential of sodium. The parameters τ_m,i define the time constant of activation of an outward adapting current. The parameters K_i define a scaling factor in the activation on an outward adapting current.

C = 20pF	gL = 2.8nS	EL(i≠5) = −60mV	EL(i=5) = −61.7mV
gI = 60nS	gE = 10nS	EI = −75mV	EE = 0mV
gK = 5nS	EK = −85mV	gNaP = 5nS	ENa = 50mV
gAD = 10nS	τm23 = 2s	τm4 = 1s	K2,3 = 1
K4 = 3