Figure 3.
Sucrose preference during (A) Week three of UCMS (day 22), (B) following 11 days of aticaprant treatment (day 33), and (C) following a recovery period of 15 days post cessation of UCMS and 10 days post aticaprant treatment cessation (day 43). The percentage of sucrose preference (sucrose consumption/(sucrose + water consumption) did not differ at baseline (NS/Vehicle = 86.1 ± 1.1; NS/Aticaprant = 85.5 ± 1.4; UCMS/Vehicle = 85.1 ± 1.5; UCMS/Aticaprant = 85.9 ± 1.5). The * symbol denotes significant differences between UCMS-treated mice and their respective no stress (NS) controls (*p < 0.05; **p ≤ 0.01). The # symbol denotes significant differences between UCMS-treated mice given aticaprant or vehicle (#p < 0.05).