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. Author manuscript; available in PMC: 2021 Dec 1.
Published in final edited form as: Biochem Pharmacol. 2020 Oct 10;182:114280. doi: 10.1016/j.bcp.2020.114280

Fig. 2.

Fig. 2.

Effects of RK-33 treatment on SG disassembly. (A–B) SG disassembly was examined by Immunofluorescence with anti-G3BP1 (red) and anti-DDX3 (green). Scale bar, 10 µm. Cells were subjected to 1 h of 0.5 mM arsenite pre-treatment followed by media replacement to recover for 30 min, 60 min, and 90 min in the (A) absence or (B) presence of 6 µM RK-33. (C and D) Time course distributions of G3BP1 granules either in absence (lighter red) or presence (darker red) of RK-33. (E and F) Time course distributions of DDX3 granules either in absence (lighter green) or presence (darker green) of RK-33. (C and E) shows density plots and (D and F) shows box-and-whisker plots. The boxes cover 50% of data, and lines within boxes indicate median values. The Wilcoxon Signed-Rank Test was used to calculate statistical significance (* p < 0.05; ** p < 0.01; *** p < 0.001).