Table 2.
Association of BMI with all-cause mortality
BMI (kg/m2)1 | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
<18.5 | 18.5–24.9 | 25.0–29.9 | 30.0–34.9 | ≥35.0 | ||||||
All individuals | ||||||||||
Deaths | 84 | 335 | 184 | 93 | 83 | |||||
Person-years | 4931 | 25,796 | 12,831 | 7688 | 6056 | |||||
Individuals | 861 | 4412 | 2167 | 1284 | 1004 | |||||
HR (95% CI)2 | 1.37 (1.12 –1.69 ) | 1 (reference) | 0.80 (0.69 –0.92 ) | 0.75 (0.60 –0.93 ) | 0.80 (0.64 –1.02 ) | |||||
Males | ||||||||||
Deaths | 52 | 179 | 56 | 18 | 5 | |||||
Person-years | 3073 | 11,423 | 1815 | 608 | 271 | |||||
Individuals | 528 | 1963 | 325 | 106 | 46 | |||||
HR (95% CI)2 | 1.27 (0.95 –1.69 ) | 1 (reference) | 0.85 (0.66 –1.11 ) | 0.82 (0.57 –1.19 ) | 0.88 (0.46 –1.69 ) | |||||
Females | ||||||||||
Deaths | 32 | 156 | 128 | 75 | 78 | |||||
Person-years | 1857 | 14,373 | 11,015 | 7080 | 5785 | |||||
Individuals | 333 | 2449 | 1842 | 1178 | 958 | |||||
HR (95% CI)2 | 1.64 (1.25 –2.13 ) | 1 (reference) | 0.79 (0.66 –0.94 ) | 0.76 (0.58 –0.99 ) | 0.84 (0.64 –1.10 ) | |||||
Excluding first 2 years of follow-up | ||||||||||
Deaths | 84 | 335 | 184 | 93 | 83 | |||||
Person-years | 4931 | 25,796 | 12,831 | 7688 | 6056 | |||||
Individuals | 861 | 4412 | 2167 | 1284 | 1004 | |||||
HR (95% CI)2 | 1.34 (1.04 –1.71 ) | 1 (reference) | 0.85 (0.72 –1.01 ) | 0.84 (0.65 –1.09 ) | 0.93 (0.70 –1.22 ) | |||||
HIV negative | ||||||||||
Deaths | 33 | 140 | 82 | 42 | 38 | |||||
Person-years | 2671 | 12761 | 6996 | 4956 | 4248 | |||||
Individuals | 644 | 3053 | 1437 | 933 | 776 | |||||
HR (95% CI)2 | 1.21 (0.89 –1.65 ) | 1 (ref) | 0.76 (0.62 –0.94 ) | 0.67 (0.48 –0.91 ) | 0.65 (0.46 –0.92 ) | |||||
HIV positive | ||||||||||
Deaths | 26 | 131 | 52 | 25 | 20 | |||||
Person-years | 1055 | 6994 | 3850 | 1800 | 1095 | |||||
Individuals | 211 | 1394 | 720 | 341 | 213 | |||||
HR (95% CI)2 | 1.33 (0.98 –1.81 ) | 1 (ref) | 0.73 (0.57 –0.94 ) | 0.71 (0.49 –1.03 ) | 0.96 (0.65 –1.41 ) | |||||
HIV unknown | ||||||||||
Deaths | 25 | 64 | 50 | 26 | 25 | |||||
Person-years | 1205 | 6042 | 1985 | 932 | 712 | |||||
Individuals | 351 | 1676 | 547 | 283 | 206 | |||||
HR (95% CI)2 | 1.74 (1.21 –2.48 ) | 1 (ref) | 0.94 (0.70 –1.26 ) | 0.99 (0.63–1.55 ) | 1.03 (0.64 –1.64 ) | |||||
Unweighted for non-response | ||||||||||
HR (95% CI)3 | 1.39 (1.15 –1.67 ) | 1 (reference) | 0.80 (0.69 –0.91 ) | 0.75 (0.61 –0.92 ) | 0.81 (0.64 –1.01 ) |
All individuals | <18.5 | 18.5–<20.0 | 20.0– <22.5 | 22.5– <25.0 | 25.0–29.9 | 30.0–34.9 | ≥35 |
---|---|---|---|---|---|---|---|
Deaths | 84 | 62 | 145 | 128 | 184 | 93 | 83 |
Person-years | 4931 | 5005 | 11398 | 9393 | 12831 | 7688 | 6056 |
Individuals | 861 | 861 | 1938 | 1613 | 2167 | 1284 | 1004 |
HR (95% CI)2 | 1.37 (1.12 –1.69 ) | 1.20 (1.08 –1.33 ) | 1 (reference) | 0.91 (0.88 –0.95 ) | 0.80 (0.69 –0.92 ) | 0.80 (0.60 –0.93 ) | 0.80 (0.64 –1.02 ) |
BMI modelled as a continuous covariate by restricted cubic splines with 4 knots; deaths / person-years in each group shown for information only. HRs are presented at selected values of BMI, comparing the median value in each BMI group to BMI 22 as the reference.
HRs estimated from Cox regression; adjusted for current age (as timescale), sex, HIV status and socioeconomic status. Models were weighted to account for non-response in the 2010 survey.
HRs estimated from Cox regression as described in footnote 2, but unweighted for non-response.