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. Author manuscript; available in PMC: 2021 Jun 1.
Published in final edited form as: Obesity (Silver Spring). 2020 Oct 18;28(12):2414–2423. doi: 10.1002/oby.23005

Table 2.

Association of BMI with all-cause mortality

BMI (kg/m2)1
<18.5 18.5–24.9 25.0–29.9 30.0–34.9 ≥35.0
All individuals
 Deaths 84 335 184 93 83
 Person-years 4931 25,796 12,831 7688 6056
 Individuals 861 4412 2167 1284 1004
 HR (95% CI)2 1.37 (1.12 –1.69 ) 1 (reference) 0.80 (0.69 –0.92 ) 0.75 (0.60 –0.93 ) 0.80 (0.64 –1.02 )
Males
 Deaths 52 179 56 18 5
 Person-years 3073 11,423 1815 608 271
 Individuals 528 1963 325 106 46
 HR (95% CI)2 1.27 (0.95 –1.69 ) 1 (reference) 0.85 (0.66 –1.11 ) 0.82 (0.57 –1.19 ) 0.88 (0.46 –1.69 )
Females
 Deaths 32 156 128 75 78
 Person-years 1857 14,373 11,015 7080 5785
 Individuals 333 2449 1842 1178 958
 HR (95% CI)2 1.64 (1.25 –2.13 ) 1 (reference) 0.79 (0.66 –0.94 ) 0.76 (0.58 –0.99 ) 0.84 (0.64 –1.10 )
Excluding first 2 years of follow-up
 Deaths 84 335 184 93 83
 Person-years 4931 25,796 12,831 7688 6056
 Individuals 861 4412 2167 1284 1004
 HR (95% CI)2 1.34 (1.04 –1.71 ) 1 (reference) 0.85 (0.72 –1.01 ) 0.84 (0.65 –1.09 ) 0.93 (0.70 –1.22 )
HIV negative
 Deaths 33 140 82 42 38
 Person-years 2671 12761 6996 4956 4248
 Individuals 644 3053 1437 933 776
 HR (95% CI)2 1.21 (0.89 –1.65 ) 1 (ref) 0.76 (0.62 –0.94 ) 0.67 (0.48 –0.91 ) 0.65 (0.46 –0.92 )
HIV positive
 Deaths 26 131 52 25 20
 Person-years 1055 6994 3850 1800 1095
 Individuals 211 1394 720 341 213
 HR (95% CI)2 1.33 (0.98 –1.81 ) 1 (ref) 0.73 (0.57 –0.94 ) 0.71 (0.49 –1.03 ) 0.96 (0.65 –1.41 )
HIV unknown
 Deaths 25 64 50 26 25
 Person-years 1205 6042 1985 932 712
 Individuals 351 1676 547 283 206
 HR (95% CI)2 1.74 (1.21 –2.48 ) 1 (ref) 0.94 (0.70 –1.26 ) 0.99 (0.63–1.55 ) 1.03 (0.64 –1.64 )
Unweighted for non-response
 HR (95% CI)3 1.39 (1.15 –1.67 ) 1 (reference) 0.80 (0.69 –0.91 ) 0.75 (0.61 –0.92 ) 0.81 (0.64 –1.01 )
All individuals <18.5 18.5–<20.0 20.0– <22.5 22.5– <25.0 25.0–29.9 30.0–34.9 ≥35
 Deaths 84 62 145 128 184 93 83
 Person-years 4931 5005 11398 9393 12831 7688 6056
 Individuals 861 861 1938 1613 2167 1284 1004
 HR (95% CI)2 1.37 (1.12 –1.69 ) 1.20 (1.08 –1.33 ) 1 (reference) 0.91 (0.88 –0.95 ) 0.80 (0.69 –0.92 ) 0.80 (0.60 –0.93 ) 0.80 (0.64 –1.02 )
1

BMI modelled as a continuous covariate by restricted cubic splines with 4 knots; deaths / person-years in each group shown for information only. HRs are presented at selected values of BMI, comparing the median value in each BMI group to BMI 22 as the reference.

2

HRs estimated from Cox regression; adjusted for current age (as timescale), sex, HIV status and socioeconomic status. Models were weighted to account for non-response in the 2010 survey.

3

HRs estimated from Cox regression as described in footnote 2, but unweighted for non-response.